铜绿假单胞菌医院感染的分布与耐药性分析

目的：分析铜绿假单胞菌的临床分布及对常用抗生素的耐药性,为临床防治其感染提供依据.方法：采用细菌培养、生化分析鉴定铜绿假单胞菌,药敏实验分析其耐药性,回顾性分析其来源与科室分布.结果：2011年1月至2012年12月在某院检出铜绿假单胞菌157株,主要分布在神经科、ICU和呼吸科,痰和分泌物中检出分别占75.8％和8.3％.铜绿假单胞菌对头孢哌酮和乙基西梭霉素等敏感,对替卡西林和哌拉西林等耐药.结论：铜绿假单胞菌感染主要发生在院内神经科、ICU和呼吸科,对替卡西林和哌拉西林等抗生素耐药.

Analysis of nosocomia infection distribution and drug resistance of pseudomonas aeruginosa

Objective： To analyze the clinical distribution of pseudomonas aeruginosa and the drug resistance of commonly-used antibiotics in order to provide basis for clinical prevention and treatment of infection. Methods： Bacteria culture and biochemical analysis were used to determine the pseudomonas aeruginosa, the drug sensitivity test was used to analyze the drug resistance,and source and department distribution of pseudomonas aeruginosa were retrospectively analyzed. Results： 157 strains of pseudmonas aeruginosa detected in a certain hospital from January 2011 to December 2012 were mainly distributed in the Neurology Department, ICU and the Respiration Department. Pseudmonas aeruginosa detected from sputum and secreta specimens accounted for 75. 8% and 8.3% respectively. P. aeruginosa strains was sensitive to cefoperazone and netromycin, but had drug resistance to ticarcillin and piperacillin. Conclusion： The infection of pseudomonas aeruginosa mainly occurs in the Neurology Department, ICU and the Respiration Department, and it has drug resistance to ticarcillin and piperacillin.