Long-term benefits of monteplase before coronary angioplasty in acute myocardial infarction |
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Authors: | Inoue Teruo Nishiki Ryoichi Kageyama Manabu Chida Ryuji Hayashi Terumi Takayanagi Kan Hikichi Yutaka Node Koichi |
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Affiliation: | Department of Cardiovascular & Renal Medicine, Saga University Faculty of Medicine, Saga, Japan. inouete@med.saga-u.ac.jp |
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Abstract: | Patients with acute myocardial infarction were randomly assigned to receive direct percutaneous coronary intervention (PCI) or pretreatment with intravenous monteplase followed by PCI. Although the combination of monteplase and PCI did not alter mortality compared with direct PCI, there was a dramatic reduction in the cardiac event rate over a 2-year follow-up compared with direct PCI. |
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