经微导管注射药物治疗冠脉支架置入后慢血流和无复流的疗效观察

目的观察经微导管内注射药物对冠脉支架置入后出现慢血流和无复流的临床疗效。方法入选72例冠脉内支架置人后出现慢血流和无复流现象的急性冠脉综合征（ACS）患者，其中33例为试验组，经微导管向靶血管内依次注射硝酸甘油、替罗非班、维拉帕米等药物；回顾39例为对照组，经指引导管向靶血管内依次注射上述同样的药物，观察两组靶血管前向血流的心肌梗死溶栓试验血流分级（thrombolysisjnmyocardialinfarction，TIMI）。结果试验组治疗慢血流和无复流现象达到TIMI3级血流的有效率明显优于对照组。结论经微导管内注射药物对急性冠脉综合征患者冠脉支架置入后出现慢血流和无复流现象是一种更有效、安全的治疗途径。

Effects of in-coronary injection by micro catheter treating slow coronary artery flow and no reflow phenomenon after stents immediate implantation

Objective To observe the effects of in-coronary injection by micro catheter treating slow coronary artery flow and no reflow phenomenon after stents immediate implantation. Methods Slow coronary artery flow and no reflow phenomenon after stents immediate implantation were happened in 72 ACS （acute coronary syn- drome） patients in our Cardiac Cath Lab, 33 patients（Micro catheter group, M group） were injected nitroglycerin, tirofiban, verapamil in coronary orderly through micro catheter and other 39 patients（control group, C group） were injected nitroglycerin, tirofiban, verapamil orderly through guiding catheter. The differences of thrombolysis in my- ocardial infarction （TIMI） were compared between two groups. Resttlts Group M was superior to group C in TIMI in ACS patients after immediate stents implantation. Conclusion In-coronary injection by micro catheter treating slow coronary artery flow and no reflow phenomenon is effective and safe.