An uncommon genetic syndrome with acute renal failure in a 30-year-old diabetic patient.

Case AB is a 31-year-old man who has had type 1 diabetes since theage of 7 years, severe visual impairment and hypoacousia. InAugust 1998 he was referred to a nephrologist because of progressiveimpairment of renal function. At his last evaluation by thediabetologist, his serum creatinine, previously 1.5–1.7mg/dl, had risen to 2.4 mg/dl. During his first nephrologicalevaluation 5 days later, the patient reported oligoanuria beginningapproximately 18 h earlier. On physical examination, the patient,who manifested a modest intellectual deficit, appeared co-operativeand in good clinical condition. His blood pressure, reportedas normal in the past, was 130/85 mmHg. Cardiac and pulmonaryassessments were normal, and oedema was absent. A moderate bladderglobus was present. The only symptoms the patient reported were occasional dysuriaand urgency during the last 3 months. Glycaemic control hadbeen good