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| 咪康唑,克霉唑与利福平联合应用的抗真菌作用 | |
| 引用本文： | 高长凤 陈祖基. 咪康唑,克霉唑与利福平联合应用的抗真菌作用[J]. 眼科研究, 1991, 9(3): 161-162 |
| 作者姓名： | 高长凤 陈祖基 |
| 作者单位： | 河南省眼科研究所，河南省眼科研究所 郑州 450003，郑州 450003 |
| 摘 要： | 在联合应用利福平后,证明咪康唑和克霉唑的最低抑菌浓度比二药单独应用时分别降低60和16倍,显示利福平有增强上述二药的抗真菌作用。其中尤以对咪康唑的增强作用更为显著,为临床合理用药提供了实验依据。 |
| 关 键 词： | 甲哌利福霉素 咪康唑 克霉唑 药理 |
In Vitro Stupies of Miconazole and Clotrimazole Combined with Rifampin Against Candide Species |
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| Gao Changfeng,et al Henan Institute of Ophthalmology,Zhengzhou. In Vitro Stupies of Miconazole and Clotrimazole Combined with Rifampin Against Candide Species[J]. Chinese Ophthalmic Research, 1991, 9(3): 161-162 | |
| Authors: | Gao Changfeng et al Henan Institute of Ophthalmology Zhengzhou |
| Abstract: | The result showed that the synergistic effect was observed when miconazole and clotrimazole were combined with rifampin. Minimum inhibitory concentration (MIC) against candide species of combination was decreased 60 fold and 16 fold, respectively, than MIC obtained without rifampin. The efficacy of combination of miconazole with rifampin was more significant than clotrimazole with rifampin. |
| Keywords: | combination therapy miconazole clotrimazole rifampin. |
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