| 刺蒺藜对培养人黑素细胞增殖及黑素合成的影响 |
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| 引用本文： | 黄壮峰,解士海.刺蒺藜对培养人黑素细胞增殖及黑素合成的影响[J].中国热带医学,2009,9(4):642-643. |
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| 作者姓名： | 黄壮峰 解士海 |
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| 作者单位： | 惠州市皮肤病医院,广东,惠州,516001 |
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| 摘 要： | 目的探讨刺蒺藜对培养的人黑素瘤细胞增殖及黑素合成的影响。方法采用MTT法测定刺蒺藜对人A375黑素瘤细胞活力的影响，NaOH裂解法测定黑素合成，并与8-MOP的结果进行比较。结果0．1、0．2和0．5mg／ml刺蒺藜对于人A375黑素瘤细胞酪氨酸酶活性及黑素生成均有较强的剂量依赖性激活作用，0．2mg／ml及0．5mg／ml刺蒺藜与对照组相比有显著差异（P〈0．01）。结论刺蒺藜对于培养的人黑素瘤细胞酪氨酸酶活性及黑素生成有较强的剂量依赖性激活作用。
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| 关 键 词： | 刺蒺藜 黑素细胞 酪氨酸酶 |
Effects of Tribulus terrestris on cell proliferation and melanin synthesis in cultured human melanoma cells |
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| HUANG Zhuang-feng,XIE Shi-hai.Effects of Tribulus terrestris on cell proliferation and melanin synthesis in cultured human melanoma cells[J].China Tropical Medicine,2009,9(4):642-643. |
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| Authors: | HUANG Zhuang-feng XIE Shi-hai |
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| Institution: | Huizhou Municipal People's Hospital of Dermatology;Huizhou 516001;Guangdong;P.R.China |
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| Abstract: | Objective To investigate the effects of Tribulus terrestris on cell proliferation and melanin synthesis of cultured human melanoma cells Methods MTT method,NaOH-assay were employed to measure the cell viability,melanin synthesis of human A375 melanoma cells;tyrosinase activity was measured by utilization of L-Dopa as the substrate.Furthermore,the effects of Tribulus terrestris on human A375 melanoma cells were compared with that of 8-MOP.Results The melanin synthesis and tyrosinase activity were clearly enh... |
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| Keywords: | Tribulus terrestris Melanocytes Tyrosinase |
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