| 艾司西酞普兰联合小剂量阿立哌唑治疗伴躯体症状抑郁症的研究 |
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| 引用本文： | 夏金校,姚华华,王一冰,曹世林,甘建光,段迪,吕柏军. 艾司西酞普兰联合小剂量阿立哌唑治疗伴躯体症状抑郁症的研究[J]. 中国临床药理学与治疗学, 2011, 16(8): 929-932 |
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| 作者姓名： | 夏金校 姚华华 王一冰 曹世林 甘建光 段迪 吕柏军 |
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| 作者单位： | 绍兴市第七人民医院精神科,绍兴312000,浙江 |
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| 摘 要： | 目的:观察艾司西酞普兰联合小剂量阿立哌唑治疗伴躯体症状抑郁症的临床疗效。方法:将80例伴躯体症状抑郁症患者随机分为服用艾司西酞普兰联合小剂量阿立哌唑(简称观察组)41例和单用艾司西酞普兰(简称对照组)39例。从药物起效、症状改善时间,治疗1、2、4及8周末汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、临床疗效总评量表(CGI)有不良反应量表(TESS)评定,3个月内服药依从性、症状复燃率及DAS评定。结果:治疗后两组HAMD、SDS、CGI分值较治疗前均有显著下降,观察组下降更明显,起效与症状改善上观察组均较对照组快,两组的TESS评分差异无显著性,但治疗依从性,观察组显著高于对照组,3个月内症状的复燃率及缓解期DAS分值观察组显著低于对照组。结论:艾司西酞普兰联合小剂量阿立哌唑治疗伴躯体症状的抑郁症较单用前者更佳。
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| 关 键 词： | 艾司西酞普兰 阿立哌唑 躯体症状 抑郁症 |
Study on the escitalopram combined with low dose of aripiprazole in the treatment of depression with somatic symptoms |
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| XIA Jin-xiao,YAO Hua-hua,WANG Yi-bing,CAO Shi-lin,GAN Jian-guang,DUAN Di,LV Bo-jun. Study on the escitalopram combined with low dose of aripiprazole in the treatment of depression with somatic symptoms[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(8): 929-932 |
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| Authors: | XIA Jin-xiao YAO Hua-hua WANG Yi-bing CAO Shi-lin GAN Jian-guang DUAN Di LV Bo-jun |
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| Affiliation: | XIA Jin-xiao,YAO Hua-hua,WANG Yi-bing,CAO Shi-lin,GAN Jian-guang,DUAN Di,LV Bo-jun Department of Psychiatry,the 7th People's Hospital of Shaoxing,Shaoxing 312000,Zhejiang,China |
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| Abstract: | AIM: To explore the clinical efficacy of escitalopram combined with low dose of aripiprazole in the treatment of depression with somatic symptoms. METHODS: Eighty patients suffering from depression with somatic symptoms were randomly divided into study group(n=41) and control group(n=39),who received either escitalopram combined with low dose of aripiprazole or escitalopram only,respectively.The clinical efficacy and safety were evaluated with Hamilton Depression Rating Scale(HAMD),Self-rating Depression Sc... |
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| Keywords: | Escitalopram Aripiprazole Somatic symptoms Depression |
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