The influence of temperament on symptoms and functional outcome in people with psychosis in the Northern Finland 1966 Birth Cohort |
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| Authors: | L. Poustka G.K. Murray E. Jääskeläinen J. Veijola P. Jones M. Isohanni J. Miettunen |
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| Affiliation: | 1. Mental Health Institute, The Second Xiangya Hospital of Central South University, Key Laboratory for Mental Health of Hunan Province, Changsha, China;2. Department of Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China;3. Key Laboratory for NeuroInformation of the Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China;4. UMass Memorial Medical Center, University of Massachusetts Medical School, MA, USA;1. Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK;2. Department of Psychology, University of Sheffield, UK;3. Department of Neuroscience, University of Cologne, Germany;1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai 200030, China;2. Department of Physics, East China Normal University, Shanghai 200062, China;1. Center for Information in BioMedicine, Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China;2. Mental Health Institute of the Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan 410011, People''s Republic of China;3. The China National Clinical Research Center for Mental Health Disorders, 139 Middle Renmin Road, Changsha, Hunan 410011, People''s Republic of China;4. National Technology Institute of Psychiatry, 139 Middle Renmin Road, Changsha, Hunan 410011, People''s Republic of China;5. Key Laboratory of Psychiatry and Mental Health of Hunan Province, 139 Middle Renmin Road, Changsha, Hunan 410011, People''s Republic of China |
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| Abstract: | ![]()
ObjectiveTo describe symptom expression and functional outcome in psychotic disorders in relation with temperament traits assessed with the Temperament and Character Inventory (TCI) in a population-based sample.MethodAs part of the 31-year follow-up survey of the Northern Finland 1966 Birth Cohort, TCI temperament items were filled in by 4349 members of the cohort. In individuals with psychotic disorders, also positive and negative symptoms and outcome variables were assessed in a 35-year follow-up. Information of TCI and outcomes were available for altogether 41 individuals with psychosis.ResultReward dependence (RD) (rho = ?0.45) and Persistence (P) (rho = ?0.52) were significantly correlated with Positive and Negative Syndrome Scale (PANSS) negative symptoms. Higher P scores predicted higher social and occupational functioning (as measured by Social and Occupational Functioning Assessment Scale [SOFAS]), and higher Harm avoidance (HA) predicted a higher likelihood of being on a disability pension.ConclusionResults indicate that understanding of personality dimensions support better understanding of outcome and symptom expressions in psychotic disorders. |
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