胰腺导管内乳头状粘液性肿瘤的影像特征及其良恶性鉴别

目的 分析良、恶性胰腺导管内乳头状粘液性肿瘤(IPMN)的CT和MRI特征,探讨其对于IPMN良恶性的鉴别诊断价值.方法 选取经手术病理证实的70例IPMN患者的临床及影像资料.根据病理诊断将70例IPMN分为良性组和恶性组;筛选分析与鉴别IPMN良恶性相关的临床与影像特征,并绘制受试者工作特征曲线(ROC),评估其对...

Imaging features of intraductal papillary mucinous neoplasms of the pancreas for predicting the malignant potential

Objective To analyse the CT and MR imaging features of pancreatic intraductal papillary mucinous neoplasms(IPMNs)for differentiating benignity from malignancy.Methods Seventy histopathology-proven cases were divided into the benign and malignant groups.The clinical and imaging features related to the differential diagnosis of benign and malignant IPMNs were screened and analysed,and ROC curves were drawn to evaluate their efficacy.Results Of the 70 cases,there were 40 and 26 individuals in the benign and malignant groups,respectively.Statistical analysis showed significant differences between the two groups in the following:dispersion limitation,evaluation of CA199,main pancreatic duct dilatation≥10 mm,cyst diameter≥3 cm,mural nodule≥5 mm,solid components and tumour classification(MD-IPMN and BD-IPMN).ROC curve analysis showed that the AUC of ADC value,main pancreatic duct diameter and lesion diameter for differentiating benign and malignant IPMN were 0.866,0.716 and 0.708 respectively,and the best cut-off value was 2.61×10^-3 mm²/s,10.5 mm and 3.05 cm.The AUC of dispersion limitation,CA199 and solid components for differentiating benign and malignant IPMN were 0.788,0.759 and 0.650 respectively.Combined with the above signs,the AUC of differential diagnosis of benign and malignant IPMN was 0.964(P<0.001),the sensitivity was 91.7%,and the specificity was 90.9%.Conclusion Imaging examination has important clinical value in the diagnosis,classification and differentiation of benign and malignant IPMNs and combined with the analysis of CT and MR signs can effectively improve the diagnostic efficiency.