血液病患者血流感染病原菌回顾性分析

目的:分析解放军总医院血液科患者血流感染的主要病原菌的分布,并观察其耐药性,为临床医师的早期合理用药提供依据.方法:选取2014年1月至2017年12月212例患者286例次送检血培养阳性标本,分析患者的基本临床特征及感染病原菌的种类分布.结果:革兰阴性菌182株(63.64％)、革兰阳性菌104株(36.36％).培...

Pathogens in Bloodstream Infection in Patients with Hematological Diseases:Retrospective Analysis

Objective:To analyze the distribution and drug resistance of pathogens sampled from the patients with bloodstream infection in the department of hematology of PLA General Hospital,so as to provide evidences for clinical prevention and control infection.Methods:From January 2014 to December 2017,A total of 286 cases-time positive blood culture samples from 212 patients in the department of hematology of the General Hospital of Chinese PLA were collected.The clinical characteristics of patients and the distribution and drug resistance of pathogens were analyzed retrospectively.Results:182(63.64%) bacterial strains were Gram-negative,and the other 104(36.36%) were Grampositive.There were 88 strains of Escherichia coli(30.77%),34 strains of Pseudomonas aeruginosa(11.89%),26 strains of Klebsiella pneumoniae(9.09%),25 strains of Staphylococcus epidermidis(8.74%),20 strains of Grampositive rods(6.99%),16 strains of Staphylococcus hominis(5.59%),11 strains of Etaphylococcus haemolyticus(3.85%),10 strains of Staphylococcus aureus(3.50%),6 strains of Staphylococcus capitis(2.10%),5 strains of Acinetobacter baumannii(1.75%) and so on.Escherichia coli,Pseudomonas aeruginosa and Klebsiella pneumoniae as Gram-negative bacteria were sensitive to amikacin.Staphylococcus epidermidis and Staphylococcus aureus as Grampositive bacteria were sensitive to vancomycin and nitrofurantoin.Conclusion:The blood culture patients with bloodstream infection in department of hematology of our hospital confirmed that more infections are Gram-negative.The clinicians should choose suitable antibiotics according to the results of bacterial culture and drug sensitive test.