Importance of surgical margins in conization for cervical intraepithelial neoplasia grade III |
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| Authors: | E. F. C. Murta A. V. Resende Maria A. H. Souza Sheila J. Adad Resalla Salum |
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| Affiliation: | (1) Discipline of Gynecology and Obstetrics, Faculty of Medicine of ”Tri^angulo Mineiro”, Av. Getúlio Guaritá, s/n, Bairro Abadia, 38025-440 Uberaba, MG, Brazil e-mail: eddiemurta@mednet.com.br Tel: +55-021-34-318-5326, Fax: +55-021-34-333-8710, BR |
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| Abstract: | We conducted a retrospective study on 201 conizations for CIN III done over the last 14 years. Of these, 53 (26.4%) had involvement of the margins, 114 (56.7%) had margins free of neoplasia, and 34 (16.9%) were not evaluated. Of the 53 cases with margin involvement, 28 (52.8%) had complementary surgery and 25 (47.2%) cytological follow-up. Residual CIN was identified in the surgical specimen in 15 cases (53.6%) and microinvasion was present in 2 cases (7.1%). Of the 114 patients with margins free of neoplasia in the cone, 12 had a hysterectomy during follow-up for CIN III diagnosed by cytology and biopsy. Seven of these 12 patients (58.3%) had CIN in the surgical specimen and none had microinvasive cancer. Received: August 1998 / Accepted: 3 May 1999 |
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| Keywords: | Conization Hysterectomy Cervical intraepithelial neoplasia grade III Margin involvement Residual neoplasia |
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