Effect of abnormal levels of serum components on antibiotic activity. |
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| Authors: | B J Plotkin M Wright A Lima L Gruenberg |
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| Affiliation: | Department of Microbiology, Chicago College of Osteopathic Medicine, Downers Grove, Illinois 60515. |
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| Abstract: | ![]()
Antibiotic activity in serum from a model for type II diabetes was similar to that in normal sera or media containing cholesterol but lacking glucose, insulin, or both. The ratio of effects of broth plus obese-rat serum to effects of broth plus lean-rat serum supplemented with cholesterol approached or equaled 1. |
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