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献血人群红细胞血型意外抗体的筛选
引用本文:祝宏,洪小珍,吴亚玲,励晓涛,马开荣,兰小飞,朱发明. 献血人群红细胞血型意外抗体的筛选[J]. 中国卫生检验杂志, 2012, 0(6): 1339-1340,1343
作者姓名:祝宏  洪小珍  吴亚玲  励晓涛  马开荣  兰小飞  朱发明
作者单位:浙江省血液中心;卫生部血液安全研究重点实验室
基金项目:浙江省自然科学研究基金(Y2101289);浙江省医药卫生科研基金(2011RCB012)
摘    要:目的:分析献血人群中红细胞血型意外抗体的情况,并对抗体特性进行确认。方法:应用O型红细胞结合PK7200血型检测系统筛选红细胞血型意外抗体,利用谱细胞鉴定抗体特性。结果:在献血人群中红细胞血型意外抗体阳性率为0.025%,意外抗体以抗M和冷凝集素为主。发现两例类孟买型血型和两例p血型。结论:献血人群中存在低比例的红细胞血型意外抗体,在献血者血型检测中应加以重视。

关 键 词:献血者  意外抗体

Screening unexpected antibody of red cells blood group in the blood donors
ZHU Hong,HONG Xiao-zhen,WU Ya-ling,LI Xiao-tao,MA Kai-rong,LAN Xiao-fei,ZHU Fa-ming. Screening unexpected antibody of red cells blood group in the blood donors[J]. Chinses Journal of Health Laboratory Technology, 2012, 0(6): 1339-1340,1343
Authors:ZHU Hong  HONG Xiao-zhen  WU Ya-ling  LI Xiao-tao  MA Kai-rong  LAN Xiao-fei  ZHU Fa-ming
Affiliation:1,2(1.Blood Center of Zhejiang Province,Hangzhou 310006,China;2.Key Laboratory of Blood Safety Research,Ministry of Health,Hangzhou 310006,China)
Abstract:Objective:To determine unexpected antibody of red cells blood group in the blood donors and identify the characteristics of the antibody.Methods:The unexpected antibody was screened by O blood group cells and PK7200 system.Characteristics of the antibody were identified by panel cells..Results:The prevalence rate of unexpected antibody was 0.025% in the blood donors.The common unexpected antibodies were anti-M and cold agglutinin.Two cases with para-Bombay phenotype and two cases with p phenotype were found.Conclusion:Low prevalence of unexpected antibody existed in the blood donors.It is important to screen unexpected antibody in donor’s blood grouping.
Keywords:Blood donor  Unexpected antibody
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