| 血清游离/总前列腺特异性抗原比值在前列腺癌诊断中的应用 |
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| 引用本文： | 张国元,唐中,邓健康,周祖寅,廖涛,郭晓兰. 血清游离/总前列腺特异性抗原比值在前列腺癌诊断中的应用[J]. 医学理论与实践, 2001, 14(8): 713-714 |
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| 作者姓名： | 张国元 唐中 邓健康 周祖寅 廖涛 郭晓兰 |
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| 作者单位： | 川北医学院附院检验科四川省南充市 637000 |
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| 摘 要： | 目的:探讨血清游离态PSA(F-PSA)和总PSA(T-PSA)及游离态/总(F/T)PSA比值作为前列腺疾病诊断指标的价值。方法:采用Abbott公司AxSYM化学发光免疫分析仪自动检测未经治疗的84例前列腺增生(BPH)病人和29例前列腺癌病人血清F-PSA和T-PSA,并计算F/T比值。结果:F/T百分率值在前列腺癌组中明显低于前列腺增生组(P<0.001)。若总PSA限定于4～10μg/L范围内,应用F/T百分率值可区别前列腺癌与前列腺增生(P<0.01),而两组总PSA差异无显著意义(P>0.05)。结论:F/T百分率值可用于区别前列腺癌与前列腺增生;总PSA在4～10μg/L范围时,应用F/T百分率值较总PSA为佳。
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| 关 键 词： | 前列腺特异抗原 前列腺肿瘤 诊断 |
| 修稿时间： | 2001-03-25 |
Role of the Percentage of Serum Free to Total Prostate Specific Antigen in Diagnosis of Prostate Cancer |
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| ZHANG Guoyuan,TANG Zhong,DENG Jiankang,LIAO Tao,GUO Xiaolan. Role of the Percentage of Serum Free to Total Prostate Specific Antigen in Diagnosis of Prostate Cancer[J]. The Journal of Medical Theory and Practice, 2001, 14(8): 713-714 |
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| Authors: | ZHANG Guoyuan TANG Zhong DENG Jiankang LIAO Tao GUO Xiaolan |
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| Affiliation: | ZHANG Guoyuan,TANG Zhong,DENG Jiankang,LIAO Tao,GUO Xiaolan Department of Clinical Laboratory Science,The Hospital Affiliated to North Sichuan Medical College,Nanchong 637000 |
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| Abstract: | Objective: To evaluate serum free-PSA(F-PSA) ,total-PSA(T-PSA) and free/total (F/T) ratio as an indicator for diagnosis of prostate diseases.Method:Serum samples obtained from 84 men with untreated BPH and 29 men with prostate cancer (PC) were measured on the AxSYM with MEIA and the ratio of F/T was studied. Results:The percentages of F/T in group with PC were lower than those of BPH clearly (P< 0.001). If T-PSA is limited to 4 -10μg/L, the ratio of F/T PSA can differentiate PC from BPH(P< 0.01), while their T-PSA show no differences (P< 0.05) .Conclusion: The ratio of F/T can be used in differentiating PC from BPH, and when T-PSA levels is within between 4 ~ 10μg/L, the former is better. |
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| Keywords: | Prostate specific antigen Prostate neoplasms Diagnosis |
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