急性心肌梗死后左心室收缩功能的定量组织速度成像分析

目的:应用定量组织速度成像技术(QTVI)测定急性前壁心肌梗死(MI)后不同时段左室的收缩功能,评价再灌注治疗对急性前壁MI患者左室收缩功能的短期影响。方法:对60例初次急性前壁MI患者[心梗后再灌注治疗28例,未再灌注治疗(未再通)32例]和年龄匹配的健康人25例应用QTVI技术分别测量二尖瓣环的收缩期峰值运动速度,计算平均峰值速度(Sa)。通过Simpson方法测定并计算左室射血分数(LVEF)、左室短轴缩短率(FS)。急性前壁MI患者分别于发病后第2、4、12周进行上述测量。比较分析再灌注治疗对急性心肌梗死(AMI)患者左室收缩功能的短期影响。结果:Sa与LVEF呈显著正相关(r=0.76);AMI患者发病后第2、4、12周的Sa、LVEF、FS均低于对照组(P<0.01);再灌注组的Sa、LVEF、FS均显著优于未再通组(P<0.05-<0.01)。结论:QTVI测量二尖瓣环峰值运动速度能很好地反映左室整体收缩功能;及时有效的再灌注治疗可明显改善左室收缩功能。

Analyzing of the systolic function of left ventricular in different periods after acute myocardial infarction by quantitative tissue velocity imaging

Objective: To assess the short period effects on the systolic function of left ventricular of reperfusion therapy in acute myocardial infarction (AMI) by quantitative tissue velocity imaging (QTVI). Methods: A total of 60 patients with AMI and 25 subjects with normai LV function were studied by QTVI. The mitrai annulus systolic peak velocities and average peak velocities (Sa) were computed. Results: There was close relation between Sa and LVEF (r=0. 76).Compared with the control group, Sa. LVEF and FS of AMI patient in 2nd,4th 12th week after AMI were all significantly decreased (P<0. 01) . While Sa. LVEF and FS of reperfusion group in 2nd, 4th, 12th week were higher than those of non-reperfusion group (P<0.05-<0. 01). Conclusion: The mitrai annulus systolic peak velocities determined by QTVI can well reflect the global systolic function of left ventricular. The well reperfusion therapy can recovery the systolic function of left ventricular significantly.