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Effects of the components of hormone therapy on matrix metalloproteinases in breast-cancer cells: an in vitro study
Authors:Abdallah Maher A  Abdullah Huda I  Kang Steven  Taylor Douglas D  Nakajima Steven T  Gercel-Taylor Cicek
Affiliation:a Division of Reproductive Endocrinology, Department of Obstetrics, Gynecology, and Women’s Health, University of Louisville School of Medicine, Louisville, Kentucky
b New York Medical College, Valhalla, New York
c Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Women’s Health, University of Louisville School of Medicine, Louisville, Kentucky
Abstract:
We describe our experience of over 300 cycles of preimplantation genetic diagnosis (PGD) and report clinical pregnancy rates (35%-67%) that support using this technology to screen for genetic disorders and chromosomal abnormalities. In clinical practice for over ten years, PGD offers couples the earliest form of genetic screening and may help improve ongoing pregnancy rates in poor-prognosis patients.
Keywords:
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