冠心病病人踝/肱指数的临床研究

目的探讨住院的冠心病人群中周围动脉疾病(peripheral artery disease,PAD)的发病情况,其可能的相关因素和临床意义.方法对入选的冠心病病人收集其一般临床资料,心血管危险因素,冠脉造影病变情况等.采用DINAMAP测振法获得双侧踝动脉和肱动脉收缩压,算出踝/肱指数, 踝/肱指数<0.9表明合并有周围动脉疾病.结果共有102例入选,其中合并PAD38例,发生率37.2%.心血管危险因素中除年龄外,高血压,糖尿病等均不与CAD合并PAD相关.Logistic 回归分析表明年龄和冠脉3支血管病变是CHD合并PAD独立预测因子.结论 CHD病人中PAD的发生率较高,两者合并存在可能反映了较高的动脉粥样硬化负荷.

The significance of ankle brachial index in hospilalized patients with coronary heart disease

Objective To investigate the prevalence of peripheral artery disease (PAD) in hospitalized patients with coronary heart disease (CHD) and the risk factors related to patients with concomitant PAD and CHD.Methods The ankle-brachial index (ABI) in every consecutive hospitalized patient with CHD was measured by an useful non-invasive method.The presence of PAD was defined as an ABI of less then 0.9.Data regarding cardiovascular risk factors and the number of coronary arteries diseased by coronary angiography were collected.Results One hundred-two patients were recruited .Thirty eight patients were found PAD.Age was only associated to PAD in traditional cardiovascular risk factors in this group population.By multiple regression analysis,aging and triple vessels disease were the predictive factors to PAD.Conclusion PAD is highly prevalent in hospitalized patients with CHD and the coexistence of PAD and CHD is likely to suggest the higher atherosclerotic burden.