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| 阿立哌唑替换氯氮平治疗精神分裂症的对照研究 | |
| 引用本文： | 张秀丽,崔玉珍,杨秀双,程群. 阿立哌唑替换氯氮平治疗精神分裂症的对照研究[J]. 中国民康医学, 2006, 18(17): 753-754 |
| 作者姓名： | 张秀丽 崔玉珍 杨秀双 程群 |
| 作者单位： | 河南省焦作市精神病医院,河南,焦作,454000 |
| 摘 要： | 目的：了解阿立哌唑替换氯氮平治疗精神分裂症的有效性和安全性。方法：将氯氮平治疗4周疗效好转及以下的精神分裂症患者，共60例，随机分为阿立哌唑组和氯氮平组，疗程8周。用阳性与阴性症状量表（PANSS），大体评定量表（GAS），临床疗效总评量表病情严重程度（CGI-SI）和副反应量表（TESS）评定疗效及不良反应。结果：两组间疗效差异无显著性，阿立哌唑组无严重不良反应。结论：阿立哌唑替换氯氮平治疗精神分裂症安全有效。 |
| 关 键 词： | 阿立哌唑 氯氮平 精神分裂症 |
| 收稿时间： | 2006-03-03 |
Controlled study on aripiprazole in the treatment of schizophrenic patients who has response to clozapine |
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| ZHANG Xiu- li, CUI Yu -zhen ,YANG Xiu -shuang, et al. Controlled study on aripiprazole in the treatment of schizophrenic patients who has response to clozapine[J]. medical journal of chinese peoples health, 2006, 18(17): 753-754 | |
| Authors: | ZHANG Xiu- li CUI Yu -zhen YANG Xiu -shuang et al |
| Affiliation: | Jiaozuo Psychiatric Hospital, Jiaozuo 454000, China |
| Abstract: | Objective:To explore the therapeutic and side effects of aripiprazole in the treatment of schizophrenic patients who has response to clozapine.Methods:Sixty schizophrenic patients were treated with aripiprazole in place of clozapine.The efficacy was measured with the positive and negative symptoms scale(PANSS),global assessment scale(GAS) and clinical global impression scale(CGI-SI),while the adverse events were determined by the treatment emergent symptoms scale(TESS).Results: There were no significantly differences in therapeutic and side effects between two groups(P>0.05).Conclusions: It is suggested that aripiprazole in place of clozapine is effective exactly in the treatment of schizophrenic patients. |
| Keywords: | Aripiprazole Clozapine Schizophrenia |
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