Polarized multispectral imaging in a rigid endoscope based on elastic light scattering spectroscopy |
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| Authors: | Ji Qi Clement Barri��re Tobias C. Wood Daniel S. Elson |
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| Affiliation: | 1Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London, Exhibition Road, London SW7 2AZ, UK;2Department of Surgery and Cancer, Imperial College London, Exhibition Road, London SW7 2AZ, UK |
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| Abstract: | ![]()
Elastic light scattering spectroscopy (LSS) is widely utilized to investigate cellular structures in cultured cells and various tissues. However, few imaging systems, especially endoscopic imaging systems, can implement LSS. It is the aim of this work to create a polarized multispectral imaging system based around a rigid endoscope to detect micrometer sized particles using LSS. The instrument first validated with different sized mono-disperse polystyrene microspheres, then an image is reconstructed based on LSS which shows the differentiation of different sized microspheres. Finally a preliminary experiment is conducted to demonstrate its capability to discriminate different types of cells.OCIS codes: (170.2150) Endoscopic imaging, (290.5855) Scattering, polarization, (110.4234) Multispectral and hyperspectral imaging |
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