北京部分地区15年脑卒中事件变化趋势—WHO—SINO—MONICA研究

目的 探讨脑卒中在北京地区变化趋势。方法 采用北京地区心血管病人群监测（WHO MONICA方案）诊断标准，通过三级监测网对人群脑卒中发病进行登记监测。结果 ①北京人群15年间（1984－1988年）脑卒中标化发病率呈显著上升的趋势（＋9．0％／年，P＝0．039）。男性为（＋11．4％／年，P＝0．027），女性为（＋8．2％／年），但无显著性差异；人群脑卒中首次发作标化发病率也呈上升的趋势（＋9．1％／年，P＝0．023），男性较女性上升更明显。②人群脑卒中标化死亡呈显著下降的趋势（－6．6％／年，P＝0．042）。城市人群较农村人群下降明显。③人群脑卒中病死率下降趋势明显（－16．7％／年，P＝0．014）。女性较男性更明显。结论 人群脑卒中发病率15年来呈显著上升的趋势，主要是首次发生率的增加，并且与高血压患病率相平等，人群高血压的防治势在必行。

Trends of Stroke Events during 15 Years in Beijing(WHO-SINO-MONICA Project Studies)

Objective To explore the trends of stroke in the population aged 25～74 in Beijing area from 1984 to 1998.Methods The cases of stroke occurred in the defined population in Beijing area were continuously collected through an established monitoring system from 1984 to 1998,being as part of the MONICA(multinational monitoring of the trends and determinants for cardiovascular diseases) project and its extensional study.Results ①There was a significant increasing trend in age-standardized incidence of stroke from 1984 to 1998 years,for an annual change being +9.0%(P=0.039);the annual changes in men was significant increased but no significant difference in women.There was a significant increasing trend in the first attack age-standardized incidence of stroke at the annual changes of +9.1%(P=0.023);the men' was significant increased at+10.3%,the women' was +7.8%.②There were decreasing trends in age-standardized mortality and case fatality of stroke,the annual changes were -6.6%(P=0.042) and -16.7%(P=0.014) respectively.Conclusion There was a significant increased trend in age-standardized incidence of stroke from 1984 to 1998,mainly because of increased incidence of the first attack of stroke.It is essential to prevent hypertension in population.