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甲状腺结节晕与超声造影增强模式的关系
引用本文:张波,杨筱,赵瑞娜,姜玉新,张青,张晓燕.甲状腺结节晕与超声造影增强模式的关系[J].中国医学影像技术,2013,29(9):1438-1441.
作者姓名:张波  杨筱  赵瑞娜  姜玉新  张青  张晓燕
作者单位:中国医学科学院 北京协和医学院 北京协和医院超声诊断科, 北京 100730;中国医学科学院 北京协和医学院 北京协和医院超声诊断科, 北京 100730;中国医学科学院 北京协和医学院 北京协和医院超声诊断科, 北京 100730;中国医学科学院 北京协和医学院 北京协和医院超声诊断科, 北京 100730;中国医学科学院 北京协和医学院 北京协和医院超声诊断科, 北京 100730;中国医学科学院 北京协和医学院 北京协和医院超声诊断科, 北京 100730
基金项目:国家自然科学基金面上项目(81171354)。
摘    要:目的 探讨甲状腺结节晕和CEUS增强模式之间的关系,及两者在甲状腺良恶性结节鉴别诊断中的意义。方法 回顾性分析90个具有完整常规超声及CEUS资料的甲状腺实性或实性为主结节,其中规则晕、不规则晕、无晕者分别为30个。统计比较三者的CEUS增强模式。结果 90个甲状腺结节中,恶性病变44个,良性病变46个。具有规则晕的结节80.00%(24/30)表现为环状增强,不规则晕者56.67%(17/30)为不均匀增强,无晕的结节中76.67%(23/30)为不均匀增强;诊断甲状腺恶性结节时,不均匀增强的敏感度和特异度高于无晕;当结节无晕或不规则晕、同时存在不均匀增强时,诊断恶性结节的敏感度为84.09%(37/44),特异度为93.46%(43/46)。结论 甲状腺结节晕的不同类型对应多种CEUS增强模式,二者相结合,可以为甲状腺结节的诊断提供更多的信息。

关 键 词:甲状腺结节  超声检查    造影剂
收稿时间:2013/1/25 0:00:00
修稿时间:2013/7/10 0:00:00

Relationship between halo of the thyroid nodule and contrast-enhanced pattern of CEUS
ZHANG Bo,YANG Xiao,ZHAO Rui-n,JIANG Yu-xin,ZHANG Qing and ZHANG Xiao-yan.Relationship between halo of the thyroid nodule and contrast-enhanced pattern of CEUS[J].Chinese Journal of Medical Imaging Technology,2013,29(9):1438-1441.
Authors:ZHANG Bo  YANG Xiao  ZHAO Rui-n  JIANG Yu-xin  ZHANG Qing and ZHANG Xiao-yan
Institution:Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Abstract:Objective To explore the relationship between halo of thyroid nodules and contrast enhancement patterns during CEUS, as well as their significances in differential diagnosis of benign and malignant thyroid nodules. Methods Conventional grey-scale ultrasound and CEUS data of 90 solid or mainly solid thyroid nodules were analyzed retrospectively. According to the feature of halo, the lesions were classified into three groups (each n=30), and the contrast enhancement patterns among them were compared statistically. Results There were 44 malignant lesions and 46 benign lesions. Twenty-four nodules (24/30, 80.00%) with regular halo showed ring enhancement, while heterogeneous enhancement were observed in 56.67% (17/30) of nodules with irregular halo and 76.67% (23/30) of nodules without halo. For the sensitivity and specificity of diagnosing malignant nodules, heterogeneous enhancement pattern was better than absent halo sign. When heterogeneous enhancement coexisted with absent halo or irregular halo, the sensitivity was 84.09% (37/44), and the specificity was 93.46% (43/46). Conclusion Different halos of thyroid nodules are corresponding to several different enhancement patterns, and a combination of both can provide more information for diagnosing thyroid nodules.
Keywords:Thyroid nodule  Ultrasonography  Halo  Contrast media
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