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抗炎舒胶囊的抗炎镇痛作用的实验研究
引用本文:熊静,陆远富,邓江,吴芹,孙安盛. 抗炎舒胶囊的抗炎镇痛作用的实验研究[J]. 遵义医学院学报, 2008, 31(4): 343-344
作者姓名:熊静  陆远富  邓江  吴芹  孙安盛
作者单位:1. 贵阳中医学院第二附属医院药剂科,贵州,贵阳,550002
2. 遵义医学院,药理学教研室,贵州省基础药理重点实验室,贵州,遵义,563003
摘    要:
目的研究抗炎舒胶囊的抗炎、镇痛作用。方法采用二甲苯所致小鼠耳肿胀,醋酸致小鼠腹膜毛细血管通透性增高,棉球植入致大鼠足肉芽肿,热板法试验、冰醋酸致小鼠扭体等方法观察抗炎舒胶囊镇痛及抗炎作用。结果抗炎舒胶囊对二甲苯所致小鼠耳肿胀和大鼠棉球肉芽肿有一定的抑制作用,可明显拮抗醋酸所致小鼠腹腔毛细血管通透性增高,亦能明显提高小鼠热板法痛阈,抑制醋酸所致小鼠扭体反应次数。结论抗炎舒胶囊具有明显抗炎、镇痛作用。

关 键 词:抗炎舒胶囊  抗炎  镇痛

Analgesic action and inflammation Effect of Kang-yan shu capsule
QIONG Jin,LU Yuan-fu,OENG Jiang,WU Qin,SUN An-sheng. Analgesic action and inflammation Effect of Kang-yan shu capsule[J]. Acta Academiae Medicine Zunyi, 2008, 31(4): 343-344
Authors:QIONG Jin  LU Yuan-fu  OENG Jiang  WU Qin  SUN An-sheng
Affiliation:XIONG Jin1,LU Yuan-fu2,DENG Jiang2,WU Qin2,SUN An-sheng2 (1. The Department of Pharmacy Second Affiliated Hospital of Guiyang Traditional Chin- ese Medicine College,Guiyang,Guizhou,550002,China,2.The Department of Pharmacolo- gy,Zunyi Medical College,The key laboratory of Basic Pharmacology of Guizhou Province,Zunyi,Guizhou 563003,China)
Abstract:
Objective To investigate the anti - inflammatory and analgesic actions of Kang-yan shu capsule. Methods Analgesic action of Kang-yan shu capsule was observed by hot - plate method and acetic - acid - induced body twist method . Anti - inflammatory action of Kang-yan shu capsule was observed on the models of xylene - induced auriculars welling in mice, celiac capillary permeability in rats, cotton - induced granuloma in rats . Results Kang-yan shu capsule inhibited the acute inflammation induced by xylene,de...
Keywords:Kang-yan shu capsule  anti - Inflammatory  analgesic  
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