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| 沙培林经动脉灌注联合栓塞治疗大鼠肝癌的实验研究 | |
| 引用本文： | 黄癸卯,李鹤平,许卫国. 沙培林经动脉灌注联合栓塞治疗大鼠肝癌的实验研究[J]. 华北煤炭医学院学报, 2009, 11(2): 143-144 |
| 作者姓名： | 黄癸卯 李鹤平 许卫国 |
| 作者单位： | 1. 广东省广州市脑科医院影像科,广州,510370 2. 中山大学附属第一医院介入放射科 3. 珠海市人民医院放射科 |
| 基金项目： | 2007年广东省社会发展领域科技计划项目(项目编号:73114) |
| 摘 要： | ①目的观察沙培林联合碘化油乳剂经肝动脉灌注对实验性大鼠晚期肝癌的治疗作用。②方法建立31只二乙基亚硝胺（DEN）诱发大鼠晚期原发性肝癌模型，随机分为对照组、常规组和实验组，经胃十二指肠动脉至肝固有动脉分别灌注生理盐水、MMC（0．2mg／Kg）＋表柔吡星（1mg／Kg）＋适量超液化碘油以及沙培林（O．25mg／Kg）＋适量超液化碘油。③结果术后实验组大鼠在治疗效果、肝功能、生存率等都优于常规组，且实验组的病理性肝功能损害轻。④结论经肝动脉灌注沙培林联合碘化油乳剂对诱发性实验性大鼠晚期肝癌具有较好的治疗作用。 |
| 关 键 词： | 肝癌 沙培林 肝动脉灌注 实验研究 大鼠 |
Experimental study of liver cancer treated with sapylin-lipiodol emulsion via hepatic artery perfusion combining embolism in rats |
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| HUANG Guimao,LI Heping,XU Weiguo. Experimental study of liver cancer treated with sapylin-lipiodol emulsion via hepatic artery perfusion combining embolism in rats[J]. Journal of North China Coal Medical College, 2009, 11(2): 143-144 | |
| Authors: | HUANG Guimao LI Heping XU Weiguo |
| Affiliation: | Department of Radiology;Peoples' Hospital;Guangzhou 510370;China |
| Abstract: | Objective To observe the therapeutic efficacy of sapylin and lipiodol emulsion via hepatic artery perfusion on late liver cancer in rat.Methods 31 ats were induced by DEN into late primary liver cancer,and divided randomly into three groups:control group,common group and experimental group,then infused with normal saline,MMC(0.2mg/Kg)+THP(1mg/Kg)+ lipiodol,Sapylin(0.25mg/Kg)+lipiodol from gastroduodenal artery into hepatic artery respectively.The survival rate,general state,and the hepatic pathomorhiesm wer... |
| Keywords: | Sapylin.Hepatic artery infusion.Liver cancer in rat.Experimental study |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |