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| 阿奇霉素治疗支原体肺炎患儿临床疗效分析 | |
| 引用本文： | 许志有. 阿奇霉素治疗支原体肺炎患儿临床疗效分析[J]. 海南医学院学报, 2012, 18(2): 238-239,242 |
| 作者姓名： | 许志有 |
| 作者单位： | 海南医学院附属医院儿科,海南海口,570102 |
| 基金项目： | 中国高校医学期刊临床专项资金项目 |
| 摘 要： | 目的:探讨阿奇霉素治疗支原体肺炎患儿的临床疗效。方法:146例6个月～15岁的支原体肺炎患儿,随机分为观察组与对照组,观察组给予阿奇霉素针剂静脉滴注,10mg.kg-1.d-1,1次/d,疗程为6d;对照组给予红霉素30～50mg.kg-1.d-1,分2次静脉滴注,疗程为10d,并分析临床疗效。结果:观察组疗效明显优于对照组,两者比较差异具有统计学意义(P<0.05);且观察组胃肠道反应发生率明显低于对照组。结论:阿奇霉素治疗支原体肺炎患儿疗效显著,半衰期长且不良反应少,推荐为首选药物。 |
| 关 键 词： | 支原体肺炎 阿奇霉素 红霉素 |
Effect of azithromycin on mycoplasma pneumonia in children |
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| XU Zhi-you. Effect of azithromycin on mycoplasma pneumonia in children[J]. Journal of Hainan Medical College, 2012, 18(2): 238-239,242 | |
| Authors: | XU Zhi-you |
| Affiliation: | XU Zhi-you(Department of Pediatrics,Affiliated Hospital of Hainan Medical University,Haikou 570102,China.) |
| Abstract: | Objective: To explore the clinical efficacy of azithromycin on the treatment of mycoplasma pneumonia in children.Methods:146 children aged 6 months to 15-year-old with mycoplasma pneumonia,were randomly divided into two groups.Children in the treatment group were treated by intravenous injection of azithromycin,10 mg/kg·d,1 time/d,6 days for a course;while children in the control group were treated by erythromycin,30-50 mg/kg·d,2 times/d,10 days for a course.Clinical efficacy was observed and compared.Results: Efficacy of the treatment group was more satisfactory than the control group,and the difference was significant(P <0.05);The incidence of gastrointestinal reactions of treatment group was significantly lower than the control group.Conclusions:Azithromycin is effective on mycoplasma pneumonia.It is the first choice,with long half-life and fewer adverse reactions. |
| Keywords: | Mycoplasma pneumonia Azithromycin Erythromycin |
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