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| 蟾毒灵抗肿瘤作用机制的研究进展 | |
| 引用本文： | 毛发江,黄海燕,左玲. 蟾毒灵抗肿瘤作用机制的研究进展[J]. 上海中医药杂志, 2022, 56(2): 87-90 |
| 作者姓名： | 毛发江 黄海燕 左玲 |
| 作者单位： | 上海中医药大学附属市中医医院 上海200071 |
| 基金项目： | 上海市科委科研计划项目(19401935200);上海中医药大学预算内科研项目(2020LK065)。 |
| 摘 要： | 阐述近年来蟾毒灵抗肿瘤作用具体机制的研究进展。蟾毒灵抗肿瘤的机制主要体现在诱导肿瘤细胞凋亡、抑制肿瘤细胞增殖、抑制肿瘤血管形成等方面,同时以蟾毒灵为基础衍生的抗肿瘤药物可以优化蟾毒灵的抗肿瘤作用,减少其副作用。 |
| 关 键 词： | 蟾毒灵 抗肿瘤 作用机制 综述 |
Research progress on antitumor mechanism of bufalin |
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| MAO Fajiang,HUANG Haiyan,ZUO Ling. Research progress on antitumor mechanism of bufalin[J]. Shanghai Journal of Traditional Chinese Medicine, 2022, 56(2): 87-90 | |
| Authors: | MAO Fajiang HUANG Haiyan ZUO Ling |
| Affiliation: | (Shanghai Municipal Hospital of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200071,China) |
| Abstract: | This paper reviews the research progress on the specific mechanism of the antitumor effect of bufalin in recent years.The antitumor mechanism of bufalin is mainly reflected in the induction of tumor cell apoptosis,inhibition of tumor cell proliferation and tumor angiogenesis and so on.And the antitumor drugs derived from bufalin can optimize the antitumor effect of bufalin,and reduce side effects. |
| Keywords: | bufalin antitumor mechanism of action review |
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