布氏显微镜活血分析: 细胞流变学研究的新方法

布氏显微镜活血分析：细胞流变学研究的新方法骆秉铨＊黄荣国＊陈兴新＊细胞流变学是研究血细胞流动变形的科学，在方法学上发展了一些比较成熟的方法，但多不能直接动态观察细胞水平的真实改变，有待完善和创新。我们采用布氏多功能显微镜的活血分析法［１］，在高放大倍...

Live Blood Analysis with Bradford Variable Projection Microscopy: A New Method of Cell Rheology

Employing a method of live blood analysis with Bradford variable projection microscopy(BVPM) to observe dynamicly the rheological behavior of living blood cells of periphery blood at high magnification. The indexes including RBC membrance flowing and aggregation, WBC behavior and aggregation, platelet shape and aggregation, magnitude and amount of circulating endogenous masses were noted. Constracting 155 cases of ischemic cardio cerebrovascular diseases and 80 health persons, the results showed that there are significant abnormal indexes(besides WBC behavior) in the patients group than contrl group( P < 0.05 ￣ 0.01 ). These changes reflect the patients have activated platelets, increased aggregation of blood cells and variant microthrombus, and provide important informations for predicting prethrombus states and treating ischemical evants. This new method of cell rheology has widespread applied value.