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右美托咪啶预防全麻患者术后躁动和咽喉疼痛的临床观察
引用本文:黄庆,檀文好,黎必万,黄光俊. 右美托咪啶预防全麻患者术后躁动和咽喉疼痛的临床观察[J]. 中国医药指南, 2012, 0(25): 56-57
作者姓名:黄庆  檀文好  黎必万  黄光俊
作者单位:钦州市第二人民医院麻醉科,广西 钦州 535000
摘    要:目的探讨右美托咪啶(DEX)对全麻患者术后躁动和咽喉疼痛的预防作用。方法选择在广西钦州市第二人民医院行择期腹腔镜妇科手术患者200例,按随机数字表法将其分为A组和B组,每组100例,两组均以咪唑安定、维库溴铵、舒芬太尼、丙泊酚诱导,丙泊酚、瑞芬太尼和七氟醚维持麻醉。手术结束前30min A组DEX 0.6μg/kg10min泵入,B组相同量生理盐水10min泵入。观察记录两组患者的自主呼吸恢复时间、呼之睁眼时间、拔管时间及苏醒期患者的躁动评级、身体舒适度评分(BCS)、术后24h咽喉疼痛评级。结果两组患者手术结束后,自主呼吸恢复时间、呼之睁眼时间及拔管时间差异无显著性(P<0.05),而躁动和咽喉痛发生率A组比B组明显降低(P<0.05),身体舒适度评分(BCS)A组明显高于B组(P<0.05)。结论 DEX可有效预防全麻术后躁动和咽喉疼痛的发生。

关 键 词:右美托咪啶  全麻  术后躁动  咽喉疼痛

Right dexmedetomidine to prevent the clinical observation of anesthesia in patients with postoperative restlessness and sore throat
HUANG Qing,TAN Wen-hao,LI Bi-wan,HUANG Guang-jun. Right dexmedetomidine to prevent the clinical observation of anesthesia in patients with postoperative restlessness and sore throat[J]. Guide of China Medicine, 2012, 0(25): 56-57
Authors:HUANG Qing  TAN Wen-hao  LI Bi-wan  HUANG Guang-jun
Affiliation:(Department of Anesthesiology,Qinzhou Second People Hospital,Qinzhou 535000,China)
Abstract:Objective To study preventive effects of dexmedetomidine on restlessness and sore throat after surgery from general anesthesia.Methods 200 patients who would undergo selective gynecological operation in celoscope were randomly divided into group A and group B(n=100).Both groups received anesthesia induction with midazolam,vecuronium bromide,sufentanil and propofol,maintenance anesthesia with propofol、remifentanil and sevoflurane.Group A was intravenously injected with dexmedetomidine at 0.6μg/kg while in group B the same amount of physiological saline was administered 30 min before the end of the operation.The recovery time of spontaneous breathing,eye opening time,extubation time,rating of agitation,physical comfort score and rating of sore throat within postoperative 24 h were recorded.Results The recovery time of spontaneous breathing,eye opening time and extubation time were not significantly different(P0.05).However,the incidences of agitation and sore throat in group A were significantly lower than those in group B(P0.05).Physical comfort scores(BCS) in group A was significantly higher than those in group B(P 0.05).Conclusion Dexmedetomidine may be effective in preventing agitation and sore throat after surgery from general anesthesia.
Keywords:Dexmedetomidine  General anesthesia  Agitation after surgery  Sore throat
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