| 肿瘤干细胞及其微环境与肿瘤的耐药、复发和转移 |
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| 引用本文： | 周柰岑,徐波,刘心. 肿瘤干细胞及其微环境与肿瘤的耐药、复发和转移[J]. 国际肿瘤学杂志, 2012, 39(10): 745-747. DOI: 10.3760/cma.j.issn.1673-422X.2012.10.008 |
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| 作者姓名： | 周柰岑 徐波 刘心 |
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| 作者单位： | 1.710061,西安交通大学医学院第一附属医院血液内科;2.710061,西安交通大学医学院第一附属医院血液内科;3.710061,西安交通大学医学院第一附属医院血液内科 |
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| 摘 要： | 肿瘤干细胞(NSC)是肿瘤发生发展的根源,其特殊的微环境可通过调控NSC或者其自身变化参与肿瘤的耐药、复发和转移.根除NSC和干扰其特殊微环境可能是治疗肿瘤的新策略.
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| 关 键 词： | 肿瘤干细胞 抗药性 复发 肿瘤转移 肿瘤微环境 |
The effect of neoplastic stem cell and microenvironment on tumor drug resistance, recurrence and metastasis |
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| ZHOU Nai-cen , XU Bo , LIU Xin. The effect of neoplastic stem cell and microenvironment on tumor drug resistance, recurrence and metastasis[J]. Journal of International Oncology, 2012, 39(10): 745-747. DOI: 10.3760/cma.j.issn.1673-422X.2012.10.008 |
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| Authors: | ZHOU Nai-cen XU Bo LIU Xin |
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| Affiliation: | Department of Hematology, The First Affiliated Hospital, Medical School of Xi′an Jiaotong University, Xi′an 710061, China |
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| Abstract: | Neoplastic stem cells （NSCs）are the source of tumor occurrence and development, and its speeial mieroenvironment is involved in tumor drug resistance, recurrence and metastasis by regulating NSCs or changing itself. Eradicating NSCs and interfering the special microenvironment may be the new therapeutic strategies for cancer. |
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| Keywords: | Neoplastic stem cells Drug resistance Recurrence Neoplasm metastasis Tumor microenvironment |
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