首页 | 本学科首页   官方微博 | 高级检索  
     

上皮细胞黏附分子在肿瘤中的研究
引用本文:张启,张洪涛,张树才. 上皮细胞黏附分子在肿瘤中的研究[J]. 国际肿瘤学杂志, 2012, 39(10): 751-754. DOI: 10.3760/cma.j.issn.1673-422X.2012.10.010
作者姓名:张启  张洪涛  张树才
作者单位:1.101149,首都医科大学附属北京胸科医院肿瘤内科;2.北京市结核病胸部肿瘤研究所中心实验室
摘    要:上皮细胞黏附分子(EpCAM)是通过与核受体结合从而在基因表达调控过程中发挥重要作用.大量研究表明,EpCAM在乳腺癌、肺癌、胃癌等多种肿瘤呈过表达.EpCAM在肿瘤循环细胞富集、肿瘤发病机制以及预后作用中的研究,将有助于肿瘤靶向治疗取得新的突破.

关 键 词:肿瘤  抗体  治疗  上皮细胞黏附分子  

Epithelial cell adhesion molecule and tumor
ZHANG Qi , ZHANG Hong-tao , ZHANG Shu-cai. Epithelial cell adhesion molecule and tumor[J]. Journal of International Oncology, 2012, 39(10): 751-754. DOI: 10.3760/cma.j.issn.1673-422X.2012.10.010
Authors:ZHANG Qi    ZHANG Hong-tao    ZHANG Shu-cai
Affiliation:Department of Oncology, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China
Abstract:Epithelial cell adhesion molecules (EpCAMs) play an important role in the process of gene expression and regulation by combining with nuclear receptor. Aben'ant expression of EpCAMs has been detec- ted in different types of cancers, such as breast cancer, lung cancer, gastric cancer, and etc. The research ofEpCAMs in circulating tumor cells enrichment, tumor pathogenesis and prognosis will be conducive to achieve new breakthroughs in cancer targeted therapy.
Keywords:Neoplasms  Antibodies  Therapy  EpCAM
本文献已被 维普 万方数据 等数据库收录!
点击此处可从《国际肿瘤学杂志》浏览原始摘要信息
点击此处可从《国际肿瘤学杂志》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号