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Hypoxia‐Triggered m‐Calpain Activation Evokes Endoplasmic Reticulum Stress and Neuropathogenesis in a Transgenic Mouse Model of Alzheimer's Disease
Authors:Chun‐Yan Wang  Jing‐Wei Xie  Tao Wang  Ye Xu  Jian‐Hui Cai  Xu Wang  Bao‐Lu Zhao  Li An  Zhan‐You Wang
Affiliation:1. Department of Pathophysiology, Key Laboratory of Medical Cell Biology of Ministry of Education of China, China Medical University, , Shenyang, China;2. Medical Research Laboratory, Jilin Medical College, , Jilin, China;3. Department of Surgery, Jilin Medical College, , Jilin, China;4. Department of Histology and Embryology, Liaoning University of Traditional Chinese Medicine, , Shenyang, China;5. State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Academia Sinica, , Beijing, China;6. Department of Nutrition and Food Hygiene, School of Public Health, China Medical University, , Beijing, China
Abstract:
Keywords:Alzheimer's disease  APP/PS1 transgenic mouse  Calpain  Endoplasmic reticulum stress  Glycogen synthase kinase 3  Hypoxia  RNA interference
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