Regional distribution of β-lipotropin converting enzymes in rat pituitary and brain |
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| Authors: | Agnes Kenessey Laszlo Graf Miklos Palkovits |
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| Affiliation: | Research Institute for Pharmaceutical Chemistry, 1045 Budapest, Hungary;First Department of Anatomy, Semmelweis University, Medical School, 1450 Budapest, Hungary |
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| Abstract: | Among the brain areas studied only pars distalis and pars intermedia are found to contain β-lipotropin activating enzyme indicating that these may be the exclusive organs for a physiologically significant conversion of β-lipotropin into β-endorphin. β-Endorphin inactivating enzyme is found to be rather uniformly distributed in all the pituitary and brain regions, α- and γ-endorphins are presumably formed by the action of this enzyme on β-endorphin. |
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| Keywords: | β -lipotropin β -lipotropin activating enzyme β -endorphin β -endorphin inactivating enzyme Regional distribution |
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