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微生物相关的免疫抑制剂
引用本文:钟传青,曹广祥,张子成,周宗仪,江曙.微生物相关的免疫抑制剂[J].中国药事,2007,21(6):436-439.
作者姓名:钟传青  曹广祥  张子成  周宗仪  江曙
作者单位:1. 鲁南制药集团股份有限公司,临沂,276006
2. 南京中医药大学药学院
摘    要:主要介绍了几种微生物产生的免疫抑制剂。从发现时间、结构、作用机制等方面将各种免疫抑制剂作了比较,对其适应症、副作用等进行了阐述。大环内酯类、杂环类、直链类、芳香族类免疫抑制剂各有其特点,在治疗器官移植、自身免疫系统疾病等方面发挥着不同的作用。

关 键 词:免疫抑制剂  器官移植  作用机制  副作用
文章编号:1002-7777(2007)06-0436-04

Immunosuppressant Produced by Microbes
Zhong Chuanqing,Cao Guangxiang,Zhang Zicheng,Zhou Zongyi,Jiang Shu.Immunosuppressant Produced by Microbes[J].Chinese Pharmaceutical Affairs,2007,21(6):436-439.
Authors:Zhong Chuanqing  Cao Guangxiang  Zhang Zicheng  Zhou Zongyi  Jiang Shu
Institution:Lunan Pharmaceutical Group Corporation, Linyi 276006; 1 Medicine Institute, Nanjing University of Traditional Chinese Medicine
Abstract:Several immunosuppressant produced with microbes are introduced in this article. The immunosuppressant are compared in detecting time, structure, effecting mechanism, etc. Their indication and side effects are expatiated on. So the characteristic of the immunosuppressant are deeply formulated. Macrolide, heterocycle, straight chain, aromatic immunosuppressant play different role in organ transplantation and autoimmune diseases.
Keywords:immunosuppressant  organ transplantation  effecting mechanism  side effect
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