Hereditary protein C deficiency and portal-vein thrombosis |
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Authors: | J N dos Santos A M e Silva P Alexandrino T Saldanha M O Carrageta E Ferreira F de Pádua |
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Affiliation: | Department IV, Santa Maria University Hospital, Lisbon, Portugal. |
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Abstract: | Inherited defects of the natural coagulation inhibitors predispose patients to thrombosis. These disorders have similar clinical presentations with a strong family history of thrombosis, episodes of recurrent venous thromboembolism, beginning in early adulthood. We report a case of upper gastrointestinal bleeding in a patient with portal hypertension due to portal-vein thrombosis secondary to hereditary protein C deficiency, an association that has seldom been reported. |
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