|
|||||
|
|
Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease |
|
| Authors: | Jean Yves Douet Saima Zafar Armand Perret-Liaudet Caroline Lacroux Séverine Lugan Naima Aron Herve Cassard Claudia Ponto Fabien Corbière Juan Maria Torres Inga Zerr Olivier Andreoletti |
| Abstract: | We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies. |
| Keywords: | Creutzfeldt-Jakob disease CJD vCJD sCJD prions blood infectivity transmissible spongiform encephalopathy TSE |