冠心病合并血糖异常患者冠状动脉病变特点分析

目的探讨冠状动脉粥样硬化性心脏病（冠心病）合并血糖异常患者冠状动脉病变的特点。方法对我院行冠状动脉造影术确诊为冠心病的236例患者临床资料进行回顾性分析，其中血糖异常组114例，血糖正常组122例，对其临床特点和冠状动脉造影结果进行对比分析。结果两组患者年龄、性别比、吸烟史、体质指数、高密度脂蛋白胆固醇、心肌梗死发生率和冠状动脉病变部位等方面比较差异均无统计学意义（均P〉0．05）。血糖异常组高血压、胆固醇、甘油三酯、低密度脂蛋白胆固醇以及载脂蛋白B水平均高于血糖正常组（P〈0．05或P〈0．01）；血糖异常组冠状动脉病变的狭窄程度重，中、重度狭窄及多支病变发生率显著增高（均P〈0．叭）。结论冠心病伴血糖异常患者多同时伴有冠心病的其他危险因素，其冠状动脉病变复杂，病变程度严重，多支病变增多。

Features of coronary artery lesion in coronary heart disease patients with pathoglycemia

Objective To investigate the features of coronary artery lesion in coronary heart disease(CHD)patients with pathoglycemia.Methods A total of 236 CHD patients diagnosed by coronary angiography(CAG)from January 2005 to January 2008 were analyzed retrospectively.Patients were divided into two groups:114 cases with pathoglycemia(pathoglycemia group)and 122 cases with normal glucose level(control group).Clinical characteristics and CAG.Results were recorded and compared between the two groups.Results There was no difference in age,sex,smoking,body mass index,high density lipoprotein cholesterol,incidence of myocardial infarction and locus of coronary artery lesion between two groups(P＞0.05).The incidence of hypertension,the level of cholesterol,triglyceride,low density lipoprotein cholesterol and apolipoprotein B in the pathoglycemia group were higher than those in the control group(P＜0.01).Compared with the control group,patients in the pathoglycemia group suffered more moderate and severe stenosis of coronary artery,muh-vessel lesions and diffuse vessel lesions(P＜0.01).Conclusion CHD patients with pathoglycemia are exposed to many other risks of CHD.The coronary lesions are more severe with more mult-vessel lesions and diffuse vessel lesions.