老年直肠癌患者预后的影响因素分析

[目的]探讨影响老年直肠癌患者预后的危险因素,为改善老年直肠癌患者预后提供参考依据。[方法]选择2007年1月-2012年1月我院收治的124例老年直肠癌患者作为研究对象,通过SPSS 17.0软件分析患者生存率及预后影响因素。[结果]124例患者1年、3年、5年生存率分别为91.13%、54.03%、23.39%,中位生存时间为41个月;Ⅰ期+Ⅱ期患者3年生存率最高,为85.71%,复发患者3年生存率最低,为11.54%;COX回归分析结果显示,TNM分期、远处转移、复发、分化程度对患者预后有显著影响(P<0.05)。[结论]TNM分期、远处转移、分化程度、复发是老年直肠癌患者独立危险因素,可作为患者预后重要评估指标。

Factors affecting the prognosis of rectal cancer in elderly patients

[Objective] To investigate the influence of risk factors in prognosis of elderly patients with rectal cancer, and to provide reference for improving the prognosis of colorectal cancer. [Methods] A total of 124 elderly cases of rectal cancer were selected in our hospital from January 2007 to January 2012 as research objects. The factors affecting the prognosis and survival rate were analyzed by the SPSS 17.0 software. [Results] The 1-, 3-, and 5-year survival rates for the 124 patients were 91.13%, 54.03%, 23.39%, the median survival time being 41 months; stage I + Ⅱ patients with 3 year survival rate accounted for the highest 85.71% of low differentiation, recurrent patients with 3 year survival rate were the lowest 11.54%. COX regression analysis showed that, TNM staging, distant metastasis, recurrence, and degree of differentiation had significant effect (P<0.05) in the prognosis of the patients [Conclusion] TNM staging, distant metastasis, degree of differentiation, and recurrence were independent risk factors in elderly patients with rectal cancer, which can be used as important evaluation indexes in the prognosis of the patients.