Risk factors and a simple scoring system for predicting bowel resection in infants with NEC |
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| Institution: | 1. Department of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, 266003 Shandong Province, China;2. Department of Physical Diagnostics, West Hospital District of Qingdao Multicipal Hospital, No. 2 Chaocheng Road, Qingdao, 266002 Shandong Province, China;3. Department of The First General Surgery, Qingdao Municipal Hospital, Qingdao University, No. 1 Jiaozhou Road, Qingdao, 266011 Shandong Province, China;1. Paris University; Siric CARPEM, Assistance Publique - Hôpitaux de Paris, Department of Gastroenterology and Digestive Oncology, Hôpital Européen Georges Pompidou, Paris, France;2. Paris University; Assistance Publique - Hôpitaux de Paris, Pathology Department, Hôpital Européen GeorgesPompidou, Paris, France;3. Paris University; Assistance Publique - Hôpitaux de Paris, Dermatology Department, Hôpital Beaujon, Clichy, France;1. Department of Internal Medicine, Infectious Diseases and Clinical Immunology, University Hospital of Reims, Avenue du Général Koenig, Reims 51092, France;2. Department of Hepato-Gastro-Enterology, University Hospital of Reims, France;3. Department of Pathology, University Hospital of Reims, France;1. Department of Gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium;2. Department of Pneumology, Cliniques Universitaires Saint-Luc, Brussels, Belgium;3. Cystic Fibrosis Reference Center, Cliniques Universitaires Saint-Luc, Brussels, Belgium;4. Department of Infectious Diseases, Cliniques Universitaires Saint-Luc, Brussels, Belgium;5. Department of Anatomopathology, Cliniques Universitaires Saint-Luc, Brussels, Belgium;1. Medical Faculty of Kunming University of Science and Technology, affiliated with The First People''s Hospital of Yunnan Province, Kunming, Yunnan, China;2. Department of Gastroenterology, the First People''s Hospital of Yunnan Province, Kunming, Yunnan, China;3. Department of Pathology, the First People''s Hospital of Yunnan Province, Kunming, Yunnan, China;1. Department of Ultrasound, the First Affiliated Hospital of Anhui Medical University, Shushan District, Hefei, Anhui, China,;2. Department of Gastroenterology, Traditional Chinese Medical Hospital of Taihe Country, No 59, Tuanjie West Road, Taihe County, Fuyang 236600, Anhui Province, China |
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| Abstract: | Background and aimsWe intended to investigate the predictors for bowel resection in infants with necrotizing enterocolitis (NEC). We further developed a scoring system for better predicting bowel resection.MethodsA total of 207 infants who underwent surgical management at Children's Hospital, Chongqing Medical University between April 2008 and December 2020 were identified for the following investigation. Bowel resection was reviewed among the infants who underwent the procedure. Potential parameters related to bowel resection were explored using a multiple logistic regression method, and then a scoring system was developed.ResultsAmong the 207 patients who underwent operative intervention that were reviewed, 109 infants underwent bowel resection. Multivariate logistic regression analysis showed that birth weight, hypotension, neutropenia, pneumoperitoneum, acidosis, and intestinal wall thickness were predictors related to the occurrence of bowel resection. A 6-point scoring system was further developed based on the obtained total coefficient, and the infants could be divided into low-, moderate- and high-risk groups according to cut values of 7 and 13.ConclusionThe results of this study demonstrated that severe NEC features and low birth weight were associated with bowel resection. The risk scoring system could accurately separate infants that were suspected to have bowel loss during surgery. |
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