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Successful treatment of Trichosporon mucoides infection with lipid complex amphotericin B and 5-fluorocytosine
Authors:Kendirli Tanil  Ciftçi Ergin  Ince Erdal  Oncel Selim  Dalgiç Nazan  Güriz Haluk  Unal Emel  Dogru Ulker
Affiliation:Divisions of Pediatric Intensive Care Unit;, Pediatric Infectious Diseases;, Pediatric Microbiology Laboratory;and Pediatric Oncology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey
Abstract:
Infections in immunocompromised children can stem from bacteria, fungi, viruses, or protozoa, but most importantly, from the host's endogenous bacterial flora. Disseminated infection caused by Trichosporon species is one of the emerging mycoses in neutropenic patients, particularly when they are treated for haematological malignancy with cytotoxic and immunosuppressive chemotherapy. We report a 15-year-old boy with acute lymphoblastic leukaemia, whose Trichosporon mucoides infection was successfully treated with lipid complex amphotericin B plus 5-fluorocytosine.
Keywords:Trichosporon mucoides    sepsis    lipid complex amphotericin B    5-fluorocytosine
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