左氧氟沙星三联疗法根治幽门螺杆菌感染

目的探讨含左氧氟沙星的三联疗法治疗幽门螺杆菌感染的有效性和安全性。方法选择62例确诊为幽门螺杆菌感染的患者,按照随机原则均分为观察组与对照组,其中观察组患者采用雷贝拉唑、阿莫西林、左氧氟沙星,对照组患者采用雷贝拉唑、阿莫西林、克拉霉素,所有患者均治疗两周后复查胃镜和快速尿素酶试验,比较两组治疗后幽门螺杆菌的根除率以及不良反应的发生率。结果观察组患者的幽门螺杆菌根除率为90.32%,对照组患者幽门螺杆菌根除率为70.97%,前者明显优于后者(P<0.05),两组患者的不良反应发生率无统计学差异(P>0.05)。结论采用左氧氟沙星联合阿莫西林和雷贝拉唑治疗幽门螺杆菌感染根除率高,用药简单方便,不良反应较少,易于患者接受,值得临床推广。

Helicobacter Pylori Eradication Treatment with Triple Therapy Containing Levofloxacin

Objective To study the efficacy and safety of triple therapy containing levofloxacin for helicobacter pylori eradication treatment.Methods 62 cases of patient with helicobacter pylori eradication treated in our hospital were selected and divided into observe group and control group randomly.Rabeprazole,Amoxicillin and Levofloxacin were used in observe group,while Rabeprazole,Amoxicillin,and Clarithromycin in control group.All the patients were given endoscopy and rapid urease test after two weeks treatment,and eradication rate of helicobacter pylori and incidence of adverse reaction were compared after treatment.Results The eradication rate of helicobacter pylori in observe group was 90.32%,while 70.97% in control group,the former was better than the latter(P<0.05),and there was no significant difference of incidence of adverse reaction in the two groups(P>0.05).Conclusion Helicobacter pylori eradication was treated by using levofloxacin combined with Rabeprazole and Amoxicillin,the eradication rate high,medication convenient,incidence of adverse reaction less,easy to accepted.It deserves clinical.