Serum anti-aquaporin 4 antibody in neuromyelitis patients is not correlated with the length of injured spinal cord segments |
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Authors: | Shirong Li Lan Chu Shuai Dong Hui Yu Zhu Xu Hao Wang |
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Affiliation: | Shirong Li,Lan Chu,Shuai Dong,Hui Yu,Zhu Xu,Hao Wang Department of Neurology,Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou Province,China |
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Abstract: | Clinical information and serum samples of 20 neuromyelitis patients and 30 patients with multiple sclerosis were collected in this study. The expression of anti-aquaporin 4 antibody in the serum of all patients was detected with an indirect immunofluorescence assay, using human embryonic kidney 293 cell line that stably express human-derived aquaporin 4 as a substrate. The characteristics of head and spinal magnetic resonance imaging were also observed in patients who had neuromyelitis and were positive for... |
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Keywords: | neuromyelitis optica multiple sclerosis aquaporin 4 antibody magnetic resonance imaging neural regeneration |
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