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Serum anti-aquaporin 4 antibody in neuromyelitis patients is not correlated with the length of injured spinal cord segments
Authors:Shirong Li  Lan Chu  Shuai Dong  Hui Yu  Zhu Xu  Hao Wang
Affiliation:Shirong Li,Lan Chu,Shuai Dong,Hui Yu,Zhu Xu,Hao Wang Department of Neurology,Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou Province,China
Abstract:
Clinical information and serum samples of 20 neuromyelitis patients and 30 patients with multiple sclerosis were collected in this study. The expression of anti-aquaporin 4 antibody in the serum of all patients was detected with an indirect immunofluorescence assay, using human embryonic kidney 293 cell line that stably express human-derived aquaporin 4 as a substrate. The characteristics of head and spinal magnetic resonance imaging were also observed in patients who had neuromyelitis and were positive for...
Keywords:neuromyelitis optica  multiple sclerosis  aquaporin 4 antibody  magnetic resonance imaging  neural regeneration  
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