Neuroprotective effects of willed-movement therapy in a rat model of cerebral ischemia/reperfusion |
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| Authors: | Deren Hou Jianfeng Liu Jinfeng Deng Zhongyang Hu Chao Feng Haixia Zhu |
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| Affiliation: | Deren Hou1,Jianfeng Liu1,Jinfeng Deng1,Zhongyang Hu1,Chao Feng2,Haixia Zhu1 1Department of Neurology,Third Xiangya Hospital,Central South University,Changsha 410013,Hunan Province,China 2Department of General Surgery,China |
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| Abstract: | ![]()
The present study established rat models of middle cerebral artery ischemia/reperfusion using the thread method.Rats performed willed-movement(climbing a ladder or wall in a box) when induced by food and water.Results revealed that Longa scores of neurological deficits significantly de-creased in the willed-movement group at 15 days after reperfusion,while expression of glial fibrillary acidic protein,neurotrophic factor-3,and growth-associated protein-43 significantly increased at 7 and 15 days after reper... |
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| Keywords: | cerebral ischemia/reperfusion glial fibrillary acidic protein growth-associated protein 43 neural regeneration willed-movement neurotrophic factor-3 |
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