枳实陷胸方合电针治疗肝胃郁热型胃食管反流病78例

目的观察枳实陷胸方合电针治疗肝胃郁热型胃食管反流病的临床疗效。方弦将符合纳人标准的153例患者按分层随机法分为治疗组78例和对照组75例，治疗组予枳实陷胸方合电针治疗，对照组予奥美拉唑合吗丁啉口服，两组均治疗30d；观察两组临床疗效及治疗前后临床症状、胃镜、病理学积分变化情况。结果治疗组总有效率为92．31％，对照组为80．00％；组间疗效比较，差异有统计学意义（P〈0．05）。治疗后治疗组各症状积分均明显减少（P〈0．05），对照组反酸烧心、胃脘灼热嘈杂症状积分下降明显（P〈0．05）；组间治疗后比较，胸痛连及两胁、口苦口干、大便不爽积分差异有统计学意义（P〈0．05）。治疗后治疗组胃镜下黏膜状况积分明显减少（P〈0．05），而对照组变化不明显；组间治疗后比较。差异有统计学意义（P〈0．05）。治疗后治疗组除上皮细胞层内炎细胞浸润外，其余各项病理积分均明显减少（P〈0．05），对照组上皮细胞层内炎细胞浸润、黏膜糜烂、溃疡形成积分减少（P〈0．05）；组间治疗后比较，鳞状上皮增生、黏膜固有层乳头延伸积分差异有统计学意义（P〈0．05）。结论枳实陷胸方合电针对肝胃郁热型胃食管反流病有较好的临床疗效，能明显改善患者的临床症状和病理变化。

Treatment of Gastroesophageal Reflux Disease with ＂Zhishi Xianxiong Decoction＂ plus Electroacupuncture in 78 Patients

Objective To observe the clinical effects of ＂Zhishi Xianxiong Decoction＂ plus electroacupuncture in the treatment of gastroesophageal reflux disease of liverstomach heat . Methods 153 patients were randomly divided into two groups ： treatment group in which 78 cases were treated with ＂Zhishi Xianxiong Decoction＂ plus electroacupuncture, and control group in which 75 cases were treated with Omeprazole and Domperidone, both with a course of 30 days. The clinical effects and scores of clinical symptoms, gastroscopic and pathoscopic results were observed. Results The total effective rate in treatment group was 92.31%, higher than 80.00% in control group（ P 〈0.05 ）. After treatments, the scores of all symptoms were lowered in treatment group（ P 〈0.05 ） ; the scores of acid regurgitation and burning stomach were lowered in control group（ P 〈0.05 ） ; there were great differences in chest pain, dryness or bitterness in the mouth between two groups（ P 〈0.05 ）. The therapeutic effect of the treatment group was better in relieving oesophageal mucous inflammation（P 〈0.05 ） ; the gastroscopic and pathoscopic results were improved more significantly in treatment group than in control group（ P 〈0.05 ）. Conclusion ＂Zhishi Xianxiong Decoction＂ plus electroacupuncture is quite effective for gastroesophageal reflux disease of liver-stomach heat.