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| 乳腺微钙化促进乳腺癌骨转移的研究进展 | |
| 引用本文： | 沈敏娟,卫敏佳,何佳颖,牛丽娜,焦凯. 乳腺微钙化促进乳腺癌骨转移的研究进展[J]. 中国病理生理杂志, 2021, 0(2): 369-374 |
| 作者姓名： | 沈敏娟 卫敏佳 何佳颖 牛丽娜 焦凯 |
| 作者单位： | 军事口腔医学国家重点实验室;阜阳师范大学教育系 |
| 基金项目： | 国家自然科学基金资助项目(No.81671012,No.81870787,No.81722015,No.81870805);军队青年培育项目(No.16QNP117)。 |
| 摘 要： | 乳腺癌是女性发病率最高的癌症,在过去的十年中,全球发病率持续上升,死亡率高居不下.最新的统计学研究表明,仅2018年,全球范围内检测出约210万乳腺癌病例,其中近63万患者死亡,因而也是女性死亡率最高的癌症[1].然而,许多癌症患者的死亡并非由于肿瘤在原发部位生长,而是在于肿瘤侵袭或转移至其他部位,其中乳腺癌最容易发生... |
| 关 键 词： | 乳腺癌 微钙化 病理性矿化 骨转移 |
Breast microcalcification promotes breast cancer metastasis to bone |
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| SHEN Min-juan,WEI Min-jia,HE Jia-ying,NIU Li-na,JIAO Kai. Breast microcalcification promotes breast cancer metastasis to bone[J]. Chinese Journal of Pathophysiology, 2021, 0(2): 369-374 | |
| Authors: | SHEN Min-juan WEI Min-jia HE Jia-ying NIU Li-na JIAO Kai |
| Affiliation: | (China State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Key Laboratory of Stomatology,Department of Oral Mucosa,School of Stomatology,Air Force Medical University,Xi'an 710032,China;Department of Education,Fuyang Normal University,Fuyang 236037,China) |
| Abstract: | Breast microcalcification is a type of pathological mineralization.Mineral usually deposits in the calcified area,which is closely related to the development of breast benign and malignant tumors.In breast lesions,microcalcification may even be a risk factor for bone metastasis of breast cancer.Once bone metastasis occurs in breast cancer,it will seriously affect the patients'quality of life and prognosis.This article reviews the mechanism among ectopic microcalcification,breast cancer and bone metastasis,and analyzes the importance of early diagnosis of breast cancer associated with microcalcification to improve clinical outcome. |
| Keywords: | Breast cancer Microcalcification Pathological mineralization Bone metastasis |
| 本文献已被 CNKI 维普 等数据库收录！ | |