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| 扩散峰度成像在直肠癌中的研究进展 | |
| 引用本文： | 卢炜荣,杨心悦,丘清,梁文. 扩散峰度成像在直肠癌中的研究进展[J]. 国际医学放射学杂志, 2022, 45(2): 184-188. DOI: 10.19300/j.2022.Z18919 |
| 作者姓名： | 卢炜荣 杨心悦 丘清 梁文 |
| 作者单位： | 1 南方医科大学珠江医院影像诊断科,广州 510220 2 南方医科大学南方医院影像中心 |
| 摘 要： | 扩散峰度成像（DKI）是一种以生物组织内水分子扩散运动呈非高斯分布为理论基础的功能MRI技术,能够描述组织内水分子扩散运动受限的真实情况,准确反映组织微观结构的复杂程度,目前已用于直肠癌的诊疗及疗效评估。介绍DKI的原理及其定量参数,概述DKI在直肠癌诊断、临床病理特征评价、分子生物学特征表征及新辅助疗效评估方面的研究进展,分析DKI在直肠癌应用中的局限性。 |
| 关 键 词： | 磁共振成像 功能磁共振成像 扩散峰度成像 直肠 直肠癌 |
| 收稿时间： | 2021-04-02 |
Research progress of diffusion kurtosis imaging in rectal cancer |
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| LU Weirong,YANG Xinyue,QIU Qing,LIANG Wen. Research progress of diffusion kurtosis imaging in rectal cancer[J]. International Journal of Medical Radiology, 2022, 45(2): 184-188. DOI: 10.19300/j.2022.Z18919 | |
| Authors: | LU Weirong YANG Xinyue QIU Qing LIANG Wen |
| Affiliation: | 1 Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou 510220, China 2 Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University |
| Abstract: | Diffusion kurtosis imaging, based on the non-Gaussian distribution of the diffusion of water molecules in bio-tissue, is a functional magnetic resonance imaging technology. It can truly describe the diffusion of water molecules in bio-tissue and accurately reflect the complexity of bio-tissue microstructures. At present, it has been applied in treatment and therapeutic assessment of rectal cancer. In this review, we introduced the basics and parameters of diffusion kurtosis imaging and summarized the recent progresses in tumor staging, and assessments of clinicopathological characteristics, molecular biological characteristics and response to neoadjuvant chemoradiotherapy. In addition, we discussed the limitations of diffusion kurtosis imaging in rectal cancer. |
| Keywords: | Magnetic resonance imaging Functional magnetic resonance imaging Diffusion kurtosis imaging Rectal Rectal cancer |
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