Evidence that Clostridium perfringens theta-toxin induces colloid-osmotic lysis of erythrocytes. |
| |
| Authors: | R W Harris P J Sims R K Tweten |
| |
| Affiliation: | Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190. |
| |
| Abstract: | ![]()
Clostridium perfringens theta-toxin was shown to lyse target erythrocytes by a colloid-osmotic mechanism. Analysis showed the onset of lysis of erythrocytes by theta-toxin could be temporarily stabilized with 0.3 M sucrose. Flow cytometry analysis of the size distribution of theta-toxin-treated erythrocytes showed swelling of the erythrocytes prior to lysis. |
| |
| Keywords: | |
|
