异种骨移植63例初步报道

１９８４年１月～１９９７年１１月，应用煮沸异种（猪、牛）骨行植骨术６３例６５次。其中用于促进骨愈合的植骨术２４次，髓内植骨内固定３７次，治疗骨髓炎４次。术后患者全部获得随访，随访时间为２个月～１１年８个月。结果表明，除５次手术感染外，其余切口均Ⅰ期愈合。认为，异种骨在人体内存在排异反应，严重者需用免疫抑制剂治疗。异种骨植骨是否成功与植骨的量和骨膜剥离的范围及方法有关。异种骨的临床应用尚有很多问题需进一步研究

PRELIMINARY REPORT OF XENOGENIC BONE GRAFT FOR SIXTY-FIVE CASES

From January 1984 to November 1997, the boiling xenogenic bone (porcine and bovine bone) was applied in 65 patients. The xenogenic bone was used to promote bone healing in 24 cases, intramedullary bone graft in 37 and osteomyelitis in 4. All of the patients were followed up for 2 to 35 months. The results showed that in five cases there was infection after operation, and all other the wounds had primary healing. The xenogenic bone seemed to induce rejection in vivo. In the sevious cases immunosuppressive treatment was often needed. The volume of the bone grafted and the extent of the periosteum being stripped seemed to be important whether xenogenic bone graft would be successful or. There were lots of problem needed investigation.