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杂交瘤细胞核糖核酸抗病毒作用
引用本文:张涛,封江南. 杂交瘤细胞核糖核酸抗病毒作用[J]. 中国免疫学杂志, 1999, 15(12): 542-544
作者姓名:张涛  封江南
作者单位:卫生部武汉生物制品研究所免疫研究室,武汉,430060
摘    要:
目的:从分泌抗狂犬病毒糖蛋白单克隆抗体(IgM)杂交瘤细胞中提取核糖核酸,研究其抗狂犬病毒的作用。方法:注射该种核糖核酸4w后后用狂犬病毒CVS株进行颅腔击。结果:该核糖核酸能明显延长的生存时间。结论:该核糖核酸对狂犬病毒且有一定的抵抗作用。

关 键 词:免疫核糖核酸 杂交瘤 单克隆抗体 狂犬病毒

Effect of anti-virus of RNA from hybridoma cell
ZHANG Tao,FENG Jiang-Nan. Effect of anti-virus of RNA from hybridoma cell[J]. Chinese Journal of Immunology, 1999, 15(12): 542-544
Authors:ZHANG Tao  FENG Jiang-Nan
Abstract:
Objective: TO Study the possibility of RNA extracted from hybridoma cell as RNA and the relation between this RNA and tranditional RNA. Methods: Extracting RNA from the hybridoma cell which secrets monoclonal antibody(IgM)against the G-Protein of Tabies virusand injecting these RNA into cranial cavity in four weeks.Results: The RNA eextracted from hybridoma cell could delay the dying of force Obviously. Conclusion: The RNA extracted from hybridoma cell had the same function as the traditional immune RNA,wihch could Provided a newnethod to study the mechanism of immune RNA.
Keywords:Immune RNA (iRNA)  Hybridoma cell  Monoclonal antibody  Rabies virus  
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