| 正交实验优化牛蒡子的提取工艺 |
| |
| 引用本文： | 卢来春,张蓉,周世文,蒋学文. 正交实验优化牛蒡子的提取工艺[J]. 儿科药学杂志, 2007, 13(1): 10-11 |
| |
| 作者姓名： | 卢来春 张蓉 周世文 蒋学文 |
| |
| 作者单位： | 第三军医大学新桥医院,重庆,400037;第三军医大学新桥医院,重庆,400037;第三军医大学新桥医院,重庆,400037;第三军医大学新桥医院,重庆,400037 |
| |
| 摘 要： | 目的:优选牛蒡子乙醇提取的最佳工艺.方法:采用L9(34)正交试验筛选醇提工艺条件,用HPLC法测定牛蒡苷的含量.结果:牛蒡子的最佳醇提条件为:乙醇浓度70%,加8倍溶剂量,回流3次,回流时间1h.结论:采用本工艺牛蒡子的活性成分牛蒡苷提取率达95.43%,工艺可行.
|
| 关 键 词： | 牛蒡子 牛蒡苷 正交设计 |
| 文章编号： | 1672-108X（2007）01-0010-02 |
| 收稿时间： | 2006-11-02 |
| 修稿时间： | 2006-12-05 |
Optimization of the technology of extracting chemical constituents from fructus arctii by orthogonal experimental design |
| |
| LU Lai-chun, ZHANG Rong, ZHOU Shi-wen, et al. Optimization of the technology of extracting chemical constituents from fructus arctii by orthogonal experimental design[J]. Journal of Pediatric Pharmacy, 2007, 13(1): 10-11 |
| |
| Authors: | LU Lai-chun ZHANG Rong ZHOU Shi-wen et al |
| |
| Abstract: | Objective:To optimize the technology of extracting chemical constituents from fructus arctii.Methods: HPLC was used to analyze the content of Arctinin,and the L_9(34) orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology.Results: The conditions of the ethanol extraction technology of extracting the constituents from Fructus arctii were 70 % ethanol, 1 hour of reflux,8-fold solvent and 3 times of extraction.Conclusions: With the extraction rate of arctiin as 95.43%,the optimized technology is stable and practical and worthy of a trial in pharmaceutical production. |
| |
| Keywords: | Fructus arctii Arctinin Orthogonal experimental design |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
