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| 脐带间充质干细胞与脐血造血干细胞临床应用的研究进展 | |
| 引用本文： | 冯磊,曹宁,梁素丽,冯春,郭镭. 脐带间充质干细胞与脐血造血干细胞临床应用的研究进展[J]. 中华妇幼临床医学杂志(电子版), 2014, 10(3): 387-392. DOI: 10.3877/cma.j.issn.1673-5250.2014.03.029 |
| 作者姓名： | 冯磊 曹宁 梁素丽 冯春 郭镭 |
| 作者单位： | 1. 100018 北京，圣释（北京）生物工程有限公司（SCLGL圣释再生医学实验室）2. 吉林大学中日联谊医院 |
| 摘 要： | 人胚胎干细胞(HESC)系及生殖细胞系的建立，被美国时代周刊(Times)列为20世纪世界十大科技成就之首。脐带间充质干细胞(UC-MSC)和脐血造血干细胞(UCB-HSC)的研究作为其中的一部分，具有广阔的临床应用前景。UC-MSC和UCB-HSC是具有自我更新、分化能力和产生多系或单系特异细胞功能的细胞，位于细胞发育谱系的顶端。笔者拟对UC-MSC和UCB-HSC的来源、生物学特点及其临床应用等方面的进展，综述如下。 |
| 关 键 词： | 间质干细胞 造血干细胞 治疗应用 |
| 收稿时间： | 2014-03-14 |
Research Progress of Clinical Application of Umbilical Cord Mesenchymal Stem Cells and Umbilical Cord Blood Hematopoietic Stem Cells |
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| Lei Feng,Ning Cao,Suli Liang,Chun Feng,Lei Guo. Research Progress of Clinical Application of Umbilical Cord Mesenchymal Stem Cells and Umbilical Cord Blood Hematopoietic Stem Cells[J]. Chinese JOurnal of Obstetrics & Gynecology and Pediatrics, 2014, 10(3): 387-392. DOI: 10.3877/cma.j.issn.1673-5250.2014.03.029 | |
| Authors: | Lei Feng Ning Cao Suli Liang Chun Feng Lei Guo |
| Affiliation: | 1. Sheng shi (Beijing) Biological Engineering Co., LTD, Beijing 100018, China |
| Abstract: | The building of human embryonic stem cell lines and germ cell lines was called the world top ten scientific and technological achievements in the 20th century by the Times of America. As one part of it, the application of umbilical cord mesenchymal stem cells (UC-MSC) and umbilical cord blood hematopoietic stem cells (UCB-HSC) has a great application prospect. UC-MSC and UCB-HSC have self-renewal, differentiation ability and produce more or single specific cell function of cells, located in the top of the cell development spectrum. This article will analyze the source, biological characteristics and clinical application of UC-MSC and UCB-HSC. |
| Keywords: | Mesenchymal stem cell Hematopoietic stem cell Therapeutic uses |
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