多囊卵巢综合征96例疗效分析

目的探讨二甲双胍联合达英-35治疗多囊卵巢综合征（PCOS）的疗效。方法对96例POCS患者给予口服二甲双胍和达英-35，连续服用3个月。观察治疗前后临床症状、性激素、血糖、胰岛素和卵巢的变化情况。结果治疗后患者临床表现改善明显；61例患者的卵巢多囊性改变明显；性激素中LH和T较治疗前均显著下降，差异有统计学意义（P〈0．01），FSH、P、PRL、E2则无明显差异（P〉0．05）；治疗前后空腹血糖水平无明显差异（P〉0．05）；治疗后患者胰岛素水平较治疗前有明显下降（P〈0．05）。结论二甲双胍联合达英-35治疗PCOS的疗效显著。

Clinical analysis of 96 cases for polycystic ovary syndrome

Objective To investigate the therapeutic effects of metformin and Dyne - 35 for polycystic ovary syndrome （PCOS）. Methods 96 patients with PCOS were studied. The changes of Clinical symptoms, Sex hormones, blood glucose,insulin,and ovaries were examined and compared Before and after treated with metformin and Dyne- 35 for 3months. Results After treatment,Clinical symptoms improved obviously;61 cases of patients with polycystic ovary changed obviously;The serum luteinizing hormone（LH） and testosterone（T） were decreased, showing statistical difference（P 〈 0.01）,but FSH,P,PRL and E2 had no change（P 〉 0.05）;Further analysis showed that before treatment and after treatment the differences of Insulin level were significant（P 〈 0.01）. Conclusion Satisfactory effect could achieved by using Metformin and Dyne - 35 for polycystic ovary syndrome （PCOS）.